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Common collocations with breakthrough in American Collocation

breakthrough noun countable

US /ˈbreɪkˌθru/

important

big
crucial
great
historic
important
major
real
significant

This could be the biggest breakthrough in malaria treatment of our generation.

of a particular type

medical
scientific
technical
technological

Progress toward medical breakthroughs is typically painstaking.

research
technology

It marks a major technology breakthrough for pupils who are blind or partially sighted.

achieve a breakthrough

achieve
make
produce

Her recent work is making breakthroughs in the investigation of genetic disorders.

be a breakthrough

be
herald
mark
represent

The discovery of the first antibiotic marked a breakthrough in modern medicine.