Collocation Dictionary

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Common collocations with affect in American Collocation

affect verb transitive

US /əˈfekt/

in a bad way

adversely
badly
deeply
detrimentally
negatively
seriously
severely

If you felt pain each time you took a step, your quality of life would be severely affected.

in a major or direct way

directly
greatly
materially
profoundly
significantly

This national pattern is not significantly affected by local variations.